There are two broad classes of plastics, thermosets and thermoplastics. A thermoplastic can readily be dissolved or melted, while a thermoset cures and changes. Once cured, it forms a tough, crosslinked network which resists solvents and will degrade instead of melting. Epoxy is a thermoset. The advice to trim or slice it off is good. Solvents like acetone or whatever, unless extremely powerful and dangerous, will have little effect on a cured epoxy. Things that easily swell and dissolve epoxies will do the same with rubber or plastic gloves or portions of your anatomy.