I have several knives. On my most expensive pocket knive, a Benchmade Axis folder, I changed the orientation of the clip so that it is away from the blade, meaning that the knife sits in the pocket with its butt sticking out.
However, on my other cheaper knives where I can't change the clip orientation, I'm okay with having the pocket knife sit in my pocket with the blade pivot side sticking up.
I find that I can work with both ways of carry, but not sure if one is definitively better than the other. On the Benchmade I changed it because I didn't want the larger end (the blade pivot side) to stick up out of the pocket. The butt end is smaller and thus less noticeable.
However, on my other cheaper knives where I can't change the clip orientation, I'm okay with having the pocket knife sit in my pocket with the blade pivot side sticking up.
I find that I can work with both ways of carry, but not sure if one is definitively better than the other. On the Benchmade I changed it because I didn't want the larger end (the blade pivot side) to stick up out of the pocket. The butt end is smaller and thus less noticeable.