First off, I should say that the majority of people here are MUCH more experienced with sharpening than myself.
With that said...
I've tried just about every kind of sharpening system, and Spyderco's Sharpmaker is the simplest and most effective that I've ever tried.
ANY kind of serrations are the easiest to sharpen! Plain edges take a bit more practice, at least for me, but they come out fine too.
I admit that I don't get the same factory edge as when the knives were new, but I'm still able to shave hair off my arm, and that's outstanding for a klutz like me.
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That's my two cents. Hey! How come you're giving me change?