I have 8 or 9 Sebenza 25's and recently picked up two large Inkosi's with micarta inlays. I've been carrying the natural micarta Inkosi for about a month now. For me, there's not a lot of difference between the two. The clip on the 25 has not bothered me at all, so the angled clip on the Inkosi has no real effect on my daily use.
The biggest difference between the two for me is that because the clip on the Inkosi doesn't ride on the lock bar, it has less tension on it,making it easier to open and it doesn't have that distinct "thunk" that the 25 has. Haven't taken the Inkosi down yet, so I really don't how much easier it will be to completely tear down and put back.