I got into making knives because of cooking and discovering Japanese kitchen knives then custom knives by western makers. There is a huge variance in techniques used by people in the kitchen as well as physical differences in end users.
A person that chokes up on the handle and uses a pinch grip (holds the blade between the pointer finger and thumb) can tolerate a bit more angle on the handle than somebody who uses a hammer grip. This is exacerbated when the knife is rocked from the tip to the heel on a cutting board (higher angle handle is awkwardly high at the start of the rocking motion). A high angle may also tend to be worse for a short person who is closer to the kitchen counter versus a tall person. A slicer needs less knuckle clearance than a chopper. And so on...
The edge profile of where, and how much curve/belly and flat spot can also be optimized for the technique of the end user. Somebody who chops most everything with a mostly straight up and down motion needs more flat spot than somebody who rocks the knife.
A rocking motion with the tip on the board has more leverage than a chopping motion up and down. In my opinion the rocking knife's optimal balance point is further back towards the top of the handle whereas a chopper needs more blade forward balance for the weight of the blade to help to chop through. The rocking knife with more belly can be left with a little more behind the edge in my opinion, but I think grind to zero (or almost) before sharpening works best on chef's knives.
Also, if you do a profile mock up in cardboard or wood, you can test how it interacts with the cutting board which helps tweak the design. I also check the knife at the point it's profiled as well as after the post-HT grind to make adjustments if it's not interacting the way I intended.
Having said that, you can make knives that work for the average user. I would say study the features and differences between popular German, French, and Japanese kitchen cutlery. For brand examples look to German: Wusthof, Henckels; French: Sabatier; Japanese: Hattori, Masamoto. There is a reason they are popular. There isn't too much innovation left to discover in kitchen knife profile and geometry in my opinion but like any kind of knifemaking it's still a challenge to make the best knife you can.