There are a variety of ways humidity/moisture and temperatures can affect a knife. But since it appears you live in New Jersey, and since this is summer, and I see on the news that it's been really hot and humid where you live, I'll assume that you're asking about hot and humid weather.
I can think of three basic ways in which a knife can be affected by weather- the materials the knife is made of can be directly affected, any lube in the knife can be directly affected, and then there are outside elements resulting from the weather.
Different materials can react to heat and moisture, metal can expand and contract in reaction to heat and cold, but the temps need to be a bit extreme. I'm not sure if it's been hot enough where you are to cause any expansion, although it's certainly possible. After all, steel bridges will expand in hot weather.
Lubricants/oils/greases can get "thicker"/stickier or "looser" depending on temperature. But since high temps tend to loosen lubricants rather than making them thicker and stickier I doubt that would be your issue, especially if there is no lubrication in your knife.
And then there are outside elements, like for example- sweat vapor. If you're carrying around a folder in your pocket all day, on a hot day, every crevice of your knife might be saturated with sweat vapor causing the parts to be coated with a salty liquid film. In liquid form sweat might not cause any noticeable issues when opening a folder, but if you take the folder out of your pocket at night, and put it on a dresser, the sweat can dry in place leaving a residue that could make a knife not open so smoothly. And even if the pivot is tight and the sweat vapor cannot penetrate the pivot, the vapor might coat the blade in the path of the ball detent causing a bit of roughness upon opening.
I've had work folders get saturated with sweat vapor and be a bit rough upon opening the next day.