Locks, locks, locks... there are so many lock designs.
I don't like liner-locks. Did at one time, but time has shown the error of that opinion. Too many random failures when used in trivial tasks.
Frame-locks are akin to liner-locks, so I treat them with caution. Still undecided as to framelocks, but leaning towards not favoring them.
My favorite is the oft-mentioned axis-lock. When it is made right, and it usually is, it is convenient, reliable, and strong.
I also like the Collins bolt-action lock, the Dalton ambi-locks (he has a few - don't know if they are his designs or not), the Spyderco Ball-Bearing lock (and the caged version), the SOG arc-lock, the plunger lock as seen on so many automatic knives, the Microtech MicroBar, and others.
Lockbacks are a "depends" choice, but usually not a favorite for primary EDC. Usually I avoid them, but there have been some inovations of late - the Triad lock and that pin in the lockbar that Extrema Ratio does make the lockback more appealling.
Balisongs - are they a lock or not? I don't consider Balisongs a lock, but instead consider Balisongs as an alternative design. Capable of great strength and reliability, though.
There are a multitude of other lock designs, some good, some not. Wish some one would write a book, more like an encyclopedia, covering as many as they can find.