Works very well for me.
On carbon steel I pre treat with Ospho.
A lot of folks use Devcon 2 hr, and I won't touch it- had a whole string of scale failures that I finally cured by throwing out the Devcon and using the Loctite.
I actually use it because it's what works best out of the materials locally available. In theory, a slow cure is going to be better than a fast cure, but in practice that's not what I've found.
One thing to watch is that all epoxies that I've worked with are quite sensitive to heat. If you have big rivets to sand down, heavy stock removal on the scales, or especially blade/tang profiling to do after glue-up, don't let any of it get more than warm!
I'm sure there are better epoxies for knifemaking, but on the other hand I haven't had any failures of the Loctite when I do my part.