The way that they are designed, the tapered ends of the screw and also of the female part sink in and bind against the holes of the frame.
I have never, ever had to use 2 allen wrenches on the new ones, and have never had troubles with getting the old ones off either. Also never had troubles with any of the screws coming loose. I actually dislike the looks of the new female pins, and IMO, they are unnecessary. IIRC, it was customer whining that played a part in the change to the new style.
My brother did lose his blade stop screw, and we are still trying to figure out how the hell that happened.
Chris says no loctite, he knows his knives.
Perhaps CRK just isnt a good fit for you?