JB Weld is tough stuff. I've used it to fix cast iron (car's manifold) and cast aluminum (motorcycle's leaking engine cover) on engines til I could come up with a better solution and then forgot about it for a long tiime so I suspect that it will hold on a knife handle unless you are batoning it through logs.
As for the pearl on the Eggerling blade I have a couple of questions (if any seem ignorant it's because I am not that experienced).
1) Is the blade heat treated already? I assume it is so drilling other holes for small pins might be tough.
2) Are there pin sized holes already drilled in the blade, or just the two like the one with the JB Weld?
3) Have you ever drilled pearl before? It would be worth reading up on it if you haven't because there are some standard approaches (Sharp drill from the back, backed up with wood I believe are a couple of those. I can't remember if you're supposed to drill fast or slow though.) Centofante's chapter on precious materials in HowTo Make Folding Knives would be worth a look.
4) Is this knife a user or a wall hanger and is it for yourself or for someone else? If I were making it for myself, to look at, not to use then I'd use some kind of tough flexible caulk to attach the slabs and avoid the danger of drilling that pearl.
5) Do you want to be able to remove the pearl in the future?
Just some random questions that occurred to me..............
Syn