I have a Whisperlite, and let me tell you, it's not the easiest stove to use. But at higher altitudes/colder weather, it really shines. As far as how to use it, I'm assuming you have not just the stove, but the fuel pump, that screws onto the fuel bottle. If you don't, you'll need to get one from somewhere. And be careful, not all the MSR pumps are compatible. For example, I have a Whisperlite, and a Dragonfly. Made the mistake of bringing my Dragonfly on a trip but didn't switch out the fuel pump from my Whisperlite. Luckily my friend had his Sierra Zip stove along just in case.
Anyway, you fill the bottle with fuel, screw the pump onto the bottle, plug the hose from the stove into the aperture on the pump, and flip the little retaining lever across the pump, so that the hose does not come loose from the fuel bottle. Next, get to pumping! It takes a bit of time to get adequate pressure, depending on how full the fuel bottle is. Expect a minimum of 40 or 50 pumps to get there. Next, open the fuel dial (located on the fuel pump that you just screwed onto the bottle) just a little bit, and let some fuel into the cup at the bottom of the stove. Turn off the fuel dial. Light the white gas in that little cup. Let the flame burn down to just about nothing, then before the flame goes out, open the fuel dial again to about 1/3 to 1/2 way. The stove should sputter, then start. If you just hear hissing, then your flame went out before you opened the fuel valve. If you don't hear hissing, then your pressure is lacking. Get back to pumping.
All this is much easier to demonstrate, or at least detail with pictures. The complicated and labor-intensive nature of such stoves is one reason why I went to canister or alcohol stoves for my non-mountaineering trips. Your best bet? Go to the local camp store/REI, and ask for a demo of their Whisperlite (they're bound to have one set up on display). That'll get you there quicker than following my arcane directions. Good luck.