I've got a few Spydercos (PPT, PM2, Karahawk, Terzuloa SLIPIT, Vallotton, Caspian Salt 2...it seems like I'm forgetting something). The blade/handle shapes and ergonomics of each of these is vastly different. Every one of them even uses a different locking mechanism to some degree. If the Spyderco logo was removed and you showed them to someone with no prior knowledge of the knives it might be hard to guess they were all made by the same company.
yeah, the comment about all Spyderco ergonomics being the same is odd to me. one of the primary strengths of Spyderco's catalog is the enormous number of options for handle and blade shapes.