Over time, those orange handles save lots of unecessary aggravation looking for the inevitably misplaced knife. If you want to greatly reduce the chance of losing your knife in the woods, they are VERY practical. So far, I've been lucky and only lost one knife but have searched for misplaced knives frequently.
But the practicality of orange clashes with a desire to blend in harmoniously. And camaflogue is something I think about too. So in the end, I would have to opt for one of the softer colors.