As with any design consideration with a knife, if screws are poorly thought out or executed, then I will not like them. However, I have neither a black nor white general answer to the question at hand.
Guys like Don and Chuck make fasteners work because their design is incorporated into the knife using embellishment.
Likewise, indexed slotted fasteners show a level of consideration and skill that can add to a knife's look.
Torx fasteners disallow indexing for the most part, and to me are an easy way out. Actually, except for knives which are meant to be taken apart for cleaning, I'd prefer to never see them used to build a custom knife. Unless the design incorporates their mass produced, mechanical nature, such as the recent work of Tim Galyean, that is. The mechanical look does appeal to many in this age of 'tactical' design. Maybe because guns use so many fasteners. I don't really know.
Similarly, bolsters which are not dovetailed bother me, as I think that dove tailing not only makes a knife look better, but reconfirm the importance and significance of a bolster in the first place.
If a knife is not made to be taken apart, then I would prefer to see pins holding them together, since I believe that assembling a knife in such a way is not only more permanent, but is more difficult to do well. It shows that the maker is confident in their skills assembling a knife so that it won't come loose down the road. Which, for a lot of custom knives, would never happen anyway, as they are not likely to be used. But if they are, they should easily last a lifetime or two.