Guess I'm in the minority. I have typically carried pocket knives loose in my pocket, but since I received my Laguiole a few months ago, I always carry it in the leather pouch it came with. I carry it with the tip down and with the pivot end up:
Two reasons: (1) the pouch was obviously intended to be used this way; and (2) that is how I received it from the maker. I have had no problems.
But if I carried a different knife in a pouch or slip, I might carry it the other way. For example, I would probably carry a trapper with the tip up and the pivot side down, like I carry it in my belt sheath.