depends, spyderco prototypes rarely get outta the shop, in 15 yrs i have seen exactly one, a gunting, and it sold for IIRC a bit less than $1K, BM protos on the other hand number in the hundreds, 400 to 700 or so, and unless theres something special about 'em (ie different handle material than the production) they bring only what a std model will, in some cases less (i had a axis afck proto and got less than a std axis afck as the proto was tip up RH only while the production was tip up/or down and RH or LH).
i used to collect BM protos/1st production runs/etc and while it was fun exactly 2 drew a premium from a std production FWIW ( a 710 proto w/alloy handles and a stryker with CF handles) and it didnt amount to much, $50 or so, and i have had literally dozens of the things.