The emerson karambit is the fastest out of the pocket knife made, period. Slip your finger in the hole and pull...*snap* the blade is open and ready to go, and with a positive grip... With your finger in the hole, there is no need for any thumb placement to grasp and pull. Even full autos need a button pushed and assited openers need a nudge to get them started... AFTER you have pulled it from the pocket with your thumb AND finger. The emerson karambit is a one finger draw.
Show me another knife made that can be drawn and opened with a single finger. The mini CQC7 is fast... I know, I have one, but the karambit is still faster.