There is one downside, the loss of the warranty. If you want a modded knife (I have two by Ban, and reground several myself), then you have to accept that own your own warranty, and have to trust the INFI and your common sense to avoid damage.
I think it's good to re-state that caveat from time to time, primarily because it probably is a dollar-value factor on re-sale. I thought about including it in my reference to Ban's work.
The reason I didn't is that I find the Busse warranty is no longer a significant factor in how I value INFI blades, believe it or not. Certainly, when I first discovered Busse knives more than ten years ago, the warranty was supremely important to me. Then, as time went by and I saw how consistently the warranty was honored by Jerry, no-questions-asked, I was more and more drawn to Busse knives above all other alternatives.
But my experience with INFI knives has given me such confidence that I can rely on them without question in the field, that my concern about what happens if I do break one has faded, happily, to a non-issue. The reality is that I've never had to send an INFI knife in for warranty work due to damage. And the number is so small, of INFI blades you see here on the forums that are pushed far enough into insanity to actually fail--and the stresses required to break them so severe--that I doubt I ever will.
The reliable performance of a knife in the field in a life-or-death situation IS hugely important to me. And Ban has demonstrated that he has the knowledge and techniques to modify INFI blades without weakening them--at least of all the ones he's done to date, I know of none that have failed due to damage by him in the modification process. That's what I meant by "no down side", although you are certainly right that the dollar value of the warranty is forfeited.