Personal opinion only but based on experience.
I've owned only one Spyderco with a stainless handle, a Native. I gave it away. Hated it. Slippery handle with no ability to gain a decent grip with leverage for opening the knife one-handed. Couldn't hold onto it well when I did get it opened. Guy I gave it to loved it...at least for a little while. He no longer carries it either.
That has been the only disappointing Spyderco knife I've ever owned.
I've owned only one Spyderco with a stainless handle, a Native. I gave it away. Hated it. Slippery handle with no ability to gain a decent grip with leverage for opening the knife one-handed. Couldn't hold onto it well when I did get it opened. Guy I gave it to loved it...at least for a little while. He no longer carries it either.
That has been the only disappointing Spyderco knife I've ever owned.