But for the heavier weight and having to buy the bag and frame separate I just can't seem to justify the price.
there's a timberline and a duplex timberline models - my t3 has the frame permanently sewn in just like a normal backpack. the duplex cargo hauler & bikini frame is a different line and they have their own timberline bags that mount to it and other style bags too. those separate frames are designed mainly for hunters who want to haul their meat with their own meat bags and for the military guys.
also, what's nice about those separate frames though is the ability to have multiple-sized bags with just one frame to save money. i probably would've gone that route if they made bags that went down to the 20-30 liter range too.
And I can't imagine it being a $400 dollar difference.
osprey is made in vietnam (at least my kestrel 28 & 38, atmos 50 & 65 are) so if everything is made in the usa then i'm guessing that price difference will be smaller and you still have to factor in the cost difference in the materials...osprey really isn't a fair comparison with kifaru though since their competitors are tactical tailor, mystery ranch, etc. hill people gear makes backpacks with lightweight materials that are closer to osprey but i believe theirs are made in the usa too so you'll find that their prices are also much higher than osprey's.
regardless, what i advice my friends is for them to look at their existing gear/their future purchases and figure out the size pack they'll need and what their intentions are (a lot of trail miles, bring all the toys to the woods outings, day hike only or do-it-all pack, etc.). i think price range is 2nd to the last step and my review threads is for those people who are already at the last step - they've narrowed it down to this specific item and they want to see all the features to make sure it does meet what they're looking for.
you're at the 2nd to the last step so sorry this review thread won't be of much help to you. most, if not all, of my review threads focuses on the last step so you won't find a brand x vs. y vs. z comments
