TN, the thing is, the cause of accidental disengagement isn't just that the flesh of your palm accidently disengages the lock. The lockup is dependent on the liner and blade tang meeting at the right geometry. At the wrong geometry, it's easy for the liner to get lateral forces on it that overcome the friction with the blade tang ... and when that happens, the liner just slides right off. What happens when you torque the knife? Well, the frame flexes to some extent or other, and that slightly changes the liner/tang geometry, and that sometimes leads to bad things. Hence my suggestion that you avoid linerlocks completely, no matter how strong the knife's lock is when static, if torquing is something you'll be doing a lot.
For framelocks, if you're torquing clockwise, the palm of your hand actually reinforces the lockup. Counterclockwise, there are occasionally reports of disengagement (if you think about it, now your palm could be working against the lock). Not so many reports that I'm terribly worried, I carry my framelocks with confidence. But again, if I knew in advance that I'd be torquing the knife a ton? Axis lock, lockback. Compression lock probably solves the linerlock's problems, and is sound here too.
Joe