I have both. I prefer the H&K14210 over the Sequel because of the width of the handle. I also like it better than the mini-Grips because of the handle length. I can get a full 4-finger grip on the H&K... not so on the mini-Grips.
The Sequel is a nice thin knife, but it's too thin for my taste. The handle is barely wider than the blade and that makes it a difficult knife to hold for anything other than opening letters.
I really like the H&K. The only downside to me is the slight recurve on the blade. I prefer straight edges, but mine sharpens up well using the corners of my Sharpmaker. I'd highly recommend the H&K for a very nice EDC knife.