I think there's somewhat of a problem with most of the "mini" designs out there because they fail to take into account that people's hands don't get smaller, and directly rescale the knife.
Take, for example, the Spyderco Rookie. It has virtually the same handle profile that the Police does. Well, in my girlfriend's hand that's great, because she holds it the way any "normal-sized" (hehehe) person holds a Police - a "2+2" grip with 2 fingers in each of the incurving parts of the handle (hard to explain if you aren't familiar with the Police). But for normal adult male hands, the ergonomics of the Rookie no longer work. It's not uncomfortable, but there is no clear indication of where your fingers should go.
An example of downsizing done right, on the other hand, are the Calypso & Calypso Jr. In this case, the smaller knife is of somewhat different shape than the larger one. The Pivot area remains the same size - if you look at them side by side they are nearly identical for about 1" on either side of the pivot. The Jr. has a blade of the same width, but it shortens more abruptly, and the handle does similarly, placing the pinkie behind the knife instead of on it.
Basically, the question is whether you are making a smaller-scale replica of the original knife or making a knife in a similar vein that will act like the larger one but in a smaller size. The first option is better for folks with tiny hands; the second one is better for everyone else. Nevertheless, most "mini" knives choose the former. That's a shame, because a lot of thinking goes into the shape of these full-sized knives and you are throwing it away if you just "miniaturize" the knife - people's hands stay the same size!
(Why else would a bear want a pocket?)