I'm NOT a damascus steel maker/forger, but from an engineering stand point, when people say that a steel is "tough", what they means is the 1.grain size is very fine and 2. there are little to none large carbides, these two elements makes it hard for cracks or micro-fractures to initiate and moves through the steel, resulting in a blade that can bend and flex without snapping
For damascus steel, you are forge welding two different types of steel together, and the weld between the layers is a perfect place for cracks to initiate:
1. the contacts layers between the two steels can cause one to lose carbon and one gains carbon, meaning that the characteristic, specifically toughness is almost impossible to predict.
2. let's say that the welds are harder that then two steel, then you'll have stress concentration point at the monosteel layers. -> crack
3. let's say that the welds are tougher and softer, then you'll also have a stress concentration point at the weld -> crack
4. if you don't seal all the seams well enough, oxygen can get in between the layers and decarb the welds -> crack. You can look that Tyrell's damascus making, before commening the forge, he soak the billet in gasoline to fill all the pockets inside.