I use Sketchup but I have a background in GIS and my wife helped me with it (she works for her dad, who is an architect).
It's a great program for us knifemakers because it's way easier to learn than other CADD programs. However, it still requires a fair bit of computer competency. If you can't figure out the basics you can search for Sketchup tutorials.
Many waterjet companies use software that doesn't support the same file type that the free version of Sketchup will produce. In other words, don't blow hours of learning and work designing knives in sketchup and think you can send that file to your waterjet guy. If you do plan on using it for waterjet cutting then ask the contractor what file types they support. If they don't take the Sketchup format then you'll have to buy the pro version or find someone who can convert a Sketchup file to the correct file type.
If you do choose to use Sketchup, an easy way to get started is take your hand drawing, scan it, then import it into Skeptchup. You'll be able to draw your knife right on top of the hand drawing. Just be careful and measure your picture and stretch it to the correct dimensions before you start digitizing it. When I sent the file to my waterjet guy he told me he could only fit two thirds the number of knives I wanted to cut onto my sheet of steel. It turned out that my scanner distorted my picture and I drew my knives too big.