I would choose 154cm over VG-10 just because in my use they are very similar & 154cm is made on the soil I call home. Either way I prefer S30V. I think it is easily worth the extra cost usually associated with it and fairly widely used. My 154cm Grip is a great knife, but my Millie blows it away.
Like others say... Typically if you're talkin VG-10, you're likely talkin Spyderco... who always (IMO) applies a near perfect heat treat. When you're talkin 154cm... Well so many makers (custom & production) use the steel there are associated variables. BM would obviously be a more common one. I find BM's HT to be adequate though somehow difficult to rid a "wire edge" during and post sharpening. Removing that wire edge is paramount to edge holding or it will shave paper, immediately get dull, then seem sharpish again.