Certainly an I-beam is tougher than a flat plate at resisting lateral forces....however, I've yet to see a well-sharpened I-beam suitable for hunting...
Any structural engineer will tell you that if you remove material from the middle of a plate of steel, you weaken the steel in every dimension. That is why a hollow-ground piece of say, 1/4" thick steel will always be weaker than a solid 1/4" bar.
Let's dig into this I-beam idea for a bit.....
Let's say you have two pieces of steel - 2" tall and 12" long. One is 1/2" thick and the other is 1/4" thick. The 1/2" thick piece is better at resisting lateral forces. An engineer would rely on a ratio of the length to the thickness to determine this. Typically, in a building, you want a 20:1 (or less) ratio. That is, for every 20 feet that a beam has to span, you want it 1 foot (or 12 inches) deep.
In this case, the ratio (length:thickness) for the 1/2" piece is 12" : 0.5" - which is 24:1
The 1/4" piece would be 12" : 0.25" - which is 48:1
Clearly the 1/4" piece is weaker than the 1/2" piece.
Now, let's say that we have two 1/4" thick pieces. One is convex ground and the other is hollow ground (both from 1/4" barstock).
The convex grind is going to have more material to it and thus, a higher "average" thickness.
So, why hollow grind?
Let's go back to our first example - say you have a 1/2" thick piece - way too thick for a knife....but you want something that is more sturdy than your 1/4" thick piece.
So, you hollow grind the 1/2" thick piece down to 1/4" (or even 3/16") in the middle. You get the sturdiness of the 1/2" thick piece at the top and bottom - despite it being 3/16" in the middle.
Sounds like a great idea right? Let's call it the I-beam idea.
The one big problem with this line of thinking is that your typical I-beam is 10-12 inches wide and 14-24 inches deep.....which in knifemaking terms would mean that if you wanted an "I-beam Bowie" with a 2" tall blade, it would have to be at least 13/16" thick at the spine! (using the the most slender ratio: 10 inches wide, 24 inches tall I-beam)
What we're talking about with knifemaking is a very minor difference. Using the 2" tall, 1/4" thick Bowie blade example....It would be like having a 24 inch deep beam that is only 3 inches wide! Not really an I-beam any more is it?!
The most important factor in determining lateral strength in a blade of steel (all other things equal - heat treat, steel type, etc.) is the overall cross section. The greater the cross section area, the more steel, the higher average thickness, the lower the slenderness ratio.....the tougher your knife will be.
Your knife doesn't care if it's convex, flat or hollow ground. If the cross section is equivalent (all other things being equal) your knife will perform the same in a lateral forces test (within reason).
The reason that engineers specify I-beams is a lot more complicated than hammering a knife into a piece of wood and trying to bend it. There are many calculations involved including floor load, twist, shear, wind load, cross bracing, earthquake load, live load and so on.