Ummm...good question. Big difference between the "best" and one's "favorite." As far as using knives in actual work, some of us carry a knife far more than we use it. For the most part, I carry mine for protection and only use it to open boxes. If I were a hunter, I'd want a razor sharp blade with outstanding edge retention and a comfortable handle. My favorite knife for all things is a Cold Steel tanto Pro-Lite with a 440A blade. Some day I'm going to get a knife with a decent blade, but for now, size means more to me than anything. And finding a premium quality blade longer than 4 inches is kind of tough.
I reckon the best knife I have is a Benchmade Ascent. Light, tough and quality made, I do carry it often. The knife I carry that probably gets more use than any others is a Cold Steel Ready Edge, a tiny 2-inch fixed blade knife made out of crummy 420 steel. But it bites deeply into cardboard and never needs sharpening because of the little serrations. I only use my bigger knife if the cutting is going to be more serious.
I'd like to see larger folders made out of carbon steel, as I feel that corrosion really would not be a problem in my case. But there are so many to choose from.
--Confed