Very good points that are too rarely made.
The gunk in the hole is a relatively small issue though, as it is not hard to clean, and you have to clean the blade anyway...
The Spyder hole is superior to studs in offering less blade clutter. On the other hand, having had Spyderholes long before I bought any thumb stud knife, it immediately struck me how most thumb studs have an obvious, if not quite overwhelming, reach and opening effort/complexity advantage, because the stud
adds to the limited "arc of movement" of the thumb, while the Spyderhole
substracts from that reach.
Not only that, but the stud adds a slight leverage advantage to defeat the detent (or spring closure pressure in the case of lockbacks), which means that, for the same strength of detent, the knife opens faster and easier.
Spyderco makes this somewhat worse by "humping" most of its blade designs, which further increases the required thumb travel arc, especially nearing the end of the arc.
Because of this, I found that, in hurried openings, the stud is usually (depending on the slickness of the stud design, the Sebenza's stud looking way too slick to my eyes) quite a bit more secure (less travel, more reach and more leverage), as sometimes the extra reach of the Spyderco "hump" makes the thumb slip out of the "regular" small Spyderholes before locking. Not a big issue, but the faster you go, the more likely it is to happen.
A better variant of the hole was a large (but shallow) oval hole with only a small "hump", found on the excellent (and for me much missed) Cold Steel Pro-Lite. Try this knife besides any of the "humped" Spyderco designs, and the less demanding bio-mechanicals of an un-raised oval hole reach is immediately apparent.
Even the liner's thumb rest design was outstanding imho.
A flipper really solves all these minor issues, but, strangely enough, a lot of them tend to have funky designs that don't appeal to me.
Gaston