If you buy full power ammo in 10mm, it ranks as a round capable of taking medium to large game. It is Ted Nugent's favorite back up while on African Safari.
I don't think I would be shooting any large animals with a 10mm pistol. Traditionally, a back-up on an African safari included another man with a .458 bolt gun or a double rifle in even bigger calibers, and for good reason.
For EDC, I carry a 1911 in .45acp. If I'm in the backcountry, I carry a S&W 629 in .44 mag. Both rounds are easy to find and reload. With the 629 I can carry EDC with .44spl loads too. The 44 is a very versatile caliber ~;-)
The only reason I'd use a 10mm would be for LE in a H&K MP5 type weapon. JMHO.
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