Late to this. I like the large Vantage. I have several and tend to carry my 20cv/micarta version from SK Blades the most. I have seen pictures of some where the lockup is not good and the lock bar is at the far side of the blade. None of mine have this issue. I have 420 HC, 13C26, 20CV, S30, and S35 blades.
Pros
They all cut well - generally better than most flat grinds for me
They all carry great with one of the best pocket clips - all clips should be done this way
Variety of blade and handle materials available - some are good office carry, some look more tactical
The Large Vantage Select is one of the best values in a folder (< $30 for 420HC with GRN handles)
Most of the handle materials have good grip and are comfortable
Cons
None of them flip well - why do these even have flipper tabs? With some work I can get some of them to flip ok
They are pinned together - older ones had screws. I get why Buck would do this, but it's negative for me
Some have dual washers (PB + nylon). Why not just use a thicker PB washer (this may be only on the SK knife - don't recall)
The naming of these is confusing - you need to be careful when ordering
Some of the handle materials are slippery (ex: rosewood)