One thing that has'nt been said is that if your shooting skills need to be developed from the position of being a novice then is it sensible to get a "first gun" which is difficult to shoot ... or get a "first gun" which is going to enable you to learn how to shoot ... because many of the suggested pistols such as short snub nosed revolvers or compact 9mm's are some of the hardest guns to shoot ...
accurately ... and if you don't have confidence ... or pick up "fears" of recoil and muzzle flash ... not to mention "noise" because you won't have ear defenders on when carrying a pistol for real ... and some element of shooting the pistol without "pods" on needs to be part of any sensible CCW "practise" ... the liklihood of getting off on the wrong foot is high.
On the other hand ... you have a far better chance of defending yourself with a pistol you have confidence in that you can shoot ... because it is only "hits" that ultimately work in your favour ...
Mention has been made of crimson trace grips ... or laser sights ... and these are an excellent aid to working out where your "starting point" would be ... not by way of "aiming" with them but by way of watching how the dot moved on the target whilst you were shooting. It would show you how you controlled recoil ... how steadily you held the gun ... and from a defensive and learning point of view will give an indication of what is working for you.
Some may say that a self defence situation is likely to be 4-6 feet away from you ... and if you practise at this distance any large calibre gun is likely to give you "some" good solid "hits" ...
If however you start to learn by going to a range and a lot of shooting is at 20 to 25 yards and you cannot hit the paper well ... what is that going to do to your confidence and are you likely to want to carry that gun if you feel "I can't shoot it well"...
The good advice about try before you buy is excellent here ... and if you can try them and see how well the gun points and can be controlled ... then go from there and don't be afraid you might be making the wrong choice if a light weight .22 is the gun you can shoot best to start with. "Hits" are what count ... and developing skill ... I have used and still would use a .22 ...
Granted as a soldier I used it in more of an "offensive" role than "defensive" ... and the fact it is silent and I could carry a lot of rounds for a light weight penalty was why I liked it ... but it does work ! And it is a small compact package ...
In the States moderated weapons carry a $200 fee which needs paying for the privilidge (as a one off payment) but they are legal in Ohio ... and they do eliminate noise and recoil ... and for a first gun make a lot of sense.