Well, time for my monthly post. . .
I think that out of the box the Glock has reliability over the 1911.
A professionally tuned/reliabilized (?) 1911 is comparable to a Glock, at least my Kimber and RRA are. Actually, I must have owned the only G19 and G36 that ever had feed/extraction problems, and the 1911's actually are more reliable than the G19 + 36 were. More typically, I had a 26 and 23 that worked fine.
Accuracy wise, a combat (non tackdriver) 1911 and a Glock probably have the same inherent ability to place bullets in a small circle, but as mentioned before, the 1911 trigger is pretty much uncontestably easier to use.
As far as the thumb safety issue goes, I personally think it is a matter of practice. I shoot thumbs high (ie, riding the safety) so I've NEVER forgotten to wipe the safety off. It's where my thumbs just go! If you shoot with many different guns, though, you may run into problems. Oh, and you can (or at least I can) wipe off the thumb safety with the index finger on the weak hand should you be shooting with that hand for whatever reason. Yes, it is a pain.
The AD issues with Glocks are of interest to me. I can see how a thumbsnap on a holster can inadvertently get inside the trigger guard while reholstering. I reholster my 1911 with my thumb on the hammer. (I'm not a cop, just an enthusiast, in case I'm coming off as one. Hats off to you guys, by the way.)
Both are fine, strong weapons that have and are proving themselves every day. I would go with what you shoot best. Buy it and shoot lots of ammo and make it part of you. Then buy the other one for fun.
It's nice to not have flame wars over this topic.