Geeze; all those preparing or about to turn 50 raise your hands!!!
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I know a little about the NSAID's, I was treated by the same folks who treated the Dodgers for their sports injuries. They even gave me a pamphlet with a picture of a baseball player. Wow.
Anyway; when you know you will be in a high use situation, like the day before the big hike or game, start the Ibuprofen then. I believe it takes approximently three days for sufficient blood serum levels of the drug to be built up. Most people take their ibuprofen too late, and end it too early.
munk