I've owned 4 CR folders, 2 of them small Sebenzas. You will not find a better built folder anywhere, from anyone. I sold them all off in favor of Swiss Army Knives.
It all comes down to personal preference and what works for each individual.
As for ambi folders...I'm primarily right handed, but do some things left handed. Fortunately I use knives with my right hand. Guns are another story. I know how frustrating it can be finding something you can actually use with comfort.
You can make a slip joint or lock back completely ambi. Benchmade's Avis locks (and it's various clones) are another.
It all comes down to personal preference and what works for each individual.
As for ambi folders...I'm primarily right handed, but do some things left handed. Fortunately I use knives with my right hand. Guns are another story. I know how frustrating it can be finding something you can actually use with comfort.
You can make a slip joint or lock back completely ambi. Benchmade's Avis locks (and it's various clones) are another.