I don't think you can go wrong with either the Para 2 or Manix 2.
Some things to consider:
-The tips of these knives are bit thinner than other offerings. If your daily tasks include jobs that may be hard on the tip, another Spyderco might suit your needs better.
-Compression and ballbearing lock are not for everyone. In addition, keeping the ballbearing lock clean might need slightly more maintenance than frame, liner or compression locks.
-Ergonomics are different. If you prefer to cant your wrist in use, the Manix 2 could be a better choice. If you prefer to keep your wrist in a natural position in use, the Para 2 could be a better choice.