There's a small knife manufacturer up in Escanaba, MI, Bark River Knife and Tool, who made several runs of their prototypes and first production runs with orange micarta handles. While it does sound a bit, er, "different" at first, it's actually not a bad looking knife in orange.
I looked around a bit and couldn't find a decent photo, all the ones I found had poor color balance and didn't look "real". Sorry.
I also saw one of the Bark River prototypes in blue G-10 yesterday. Personally, I think blue G-10 looks pretty darn good on the right knife.
Having used an older orange handle Spyderco Rescue Jr. in "public" on a number of occasions, in spite of the serrations, people didn't seem to have a problem with it. Granted, it came out of my crash bag, and it wasn't the full-size Rescue, but the orange kinda gave it a "helpful" or "safety" persona rather than what a mean and evil black handle might have.
I'd propose that there might be a market for a Busse emergency/rescue type of knife. Hell, we can even have another naming contest...
