My knee-jerk reaction is yes. I had an 1111 that was reground to full flat* (off the Exchange, I didn't do it.) It weighed about 4.5 oz less than a stock one. It worked on the 1111 because the res-c handle and reduced tang basically turned into a BG B11, but I think it would move the balance point back significantly and make the DT very "knifey."
One think you could do to compensate would be to bob the rear talon so that you could choke back for more leverage. Improving the cutting ability at the edge might also help to make up for the loss in forward weight, but I would be cautious about heat damage and probably wouldn't go much under .03".
*The regrind turned out to have resulted in some combination of too thin (.017-.02") and a damaged ht. I killed it, but when I asked the shop a couple of questions Jerry asked me to send it in and after looking at it, insisted on making me whole even though I said I wasn't looking for warranty coverage. I was totally blown away. When Jerry says he's never denied a warranty claim, I totally believe it. He's a class act and stands behind his product completely. :thumbup: