After carrying the Wegner for over a year, the Starmate drove me crazy at first, owing to the fingerwell being cut out only on the "front" side. I had gotten used to really gripping hard into the fingerwell, and with the slab and liner left high, it dug into my index finger quite uncomfortably.
After having the back side slab and liner milled down to approximate the Wegner, I'm left with two knives that are both extremely comfortable, and extremely well balanced. They each have their plusses, and they each have very few, if any, serious minusses.
The Wegner is uncharacteristically "soft". It's lines and edges are all curves. It is a knife meant to be used hard, and is strong and comfortable in all tasks. It is heavier than the Starmate, owing to it's steel backspacer and full liner (rather than the inset liner-lock piece of the Starmate). I like both of these features, and think that they are worth their weight. The Wegner is clipped for tip-up carry. Since it Spyder drops super-fast (if you've got the handle weight, use it!), I like this arrangement. The Wegner is a natural for reverse grip.
The Starmate has a lot more straight lines and angles. It has a much more "tactical" look and feel. The thumb ramp is exceptionally well designed, and super comfortable. Because it is designed "straighter", I find the point easier to index than the Wegner, and more suited to the more common fighting styles. I do not particularly care for the "raised" lettering style on the blade. This is my first experience with CPM-440V, and I am SOLD! Having notched out the back side slab and liner, the knife is now much easier to grip and drop. This being the case, I'd also like this knife tip up.
The Wegner and the Starmate are my two current "favorite" carry knives, and although I miss one when carrying the other, it is only because I love them both, not because one is better than the other. Ah, my kids...I love them all!