The blade locking and opening action is easy, but not as easy as the "OCD open/close constantly" knifeknuts would like it. However, it is truly ambidextrous, unlike any frame lock. There are many ways to open/close it one handed, it takes awhile to get the "muscle memory" going, but after a bit, the ti-lock closes and opens as easy as a sebenza or maybe easier since its ambidextrous. Within a week of using it daily, I was opening and closing it w/o difficulty. Never bit me once.
Except that it isn't ambidextrous when it comes to putting it in your pocket...right handers only.