Another vote for Ruger semi. They are bulletproof. I have put probably 40,000 rounds though mine if not more. I have been shooting it for about 16+ years or so. Mine is a MarkI, which was used when I bought it. My dad's Mark II is great, and my brother loves his mark III government model.
The synthetic framed ones feel much lighter in the hand. My only problem with them is that with my meaty hands, when I go to eject the clip, the heel of my hand keeps it from dropping free unless I shift my grip.