So yes, I will be "disgruntled." I will be as "disgruntled" as I can be. Perhaps if I'm "disgruntled" enough, and enough other lefties are "disgruntled" enough, we could show that there is, in fact, a market for higher end knives made for lefties.
In the improbable event that Spyderco did, in fact, make a left handed version, it is unlikely that you would actually see a difference in price for the right handed version. Perhaps the left handed version would be a bit more expensive, but if they are running CNC programs to make knives, it wouldn't really cost a whole lot extra to just mirror the program to make it left handed. You can seen an example of this in the (now discontinued) left handed Spyderco Military. On some websites it is actually cheaper than a right handed version--likely a combination of the dealer's desire to get rid of something that isn't in high demand, as well as the knife having a similar enough cost to a right handed Military.