Hi Sal,
I've been watching and thinking about this for awhile, and I have a feeling that a model like this would pull/appeal to a different market than the current Spyderco ELU.
Watching the General and some other fora, there is are lots of users that bypass Spyderco because they don't like frontlocks (Spyderco's primary lock), linerlocks, or the compression lock. Look at everything from the (accursed) BM Skirmish :barf: , to Strider folders, to the Sebenza, and the ongoing popularity of framelocks in customs - whether all Ti, or Ti/G10 framelocks.
The IMO lukewarm response here is akin to the lukewarm response to the idea of a Spyderco butterfly (on this forum) - until the Butterfly market was appraised of the situation. The market that only likes Ti RILs isn't on this forum right now. It is a different buyer for the most part, it seems. The Ti RIL is a kind of cult design. We know objectively that it isn't as strong as say a steel linerlock nested in G10, or even a Ti compression framelock, but it is what that particular segment of the ELU likes.
A properly done Spyderco RIL could bring in new ELU the way the Spyderfly did. The current ELU is here because they like what Spyderco is already doing - if they wanted RILs they'd be elsewhere. It is a gamble of course. There isn't a General RIL forum for us to ask on.
There are two roads here as i see it. To make a RIL framelock sprint of a current model to treat the ELU, though we might have trouble agreeing on a model. You'd probably do better to just pick one that you'd like to do that way, and surprise everyone a month or so before it ships.
The other road is to try to do something that some of the current ELU will like, but is mostly aimed at the RIL ELU that currently doesn't own Spydercos and hasn't considered them in the past. That would probably be a new model, something that could and would compete with the aforementioned models and brands which currently comprise that market. A flagship model.
My 2 Yen.