Indeed designs can conform to the operator and have to to an extent. They can even be designed to eliminate the operator. Part of the beauty of any design, however, is to be able to optimize it's characteristics with the knowledge that individuals will have enough talent and can be trained to or will train themselves to use it effectively.
The simplest devices actually take the most talent but show the steepest learning curves. Someone's first attempt at throwing a rock or using a yo yo is a hoot and an expert a thing of wonder. The complex designs are similar, however. Teach someone to drive a manual transmission car vs. an automatic. Flying a tricycle gear light airplane vs. a tail dragger. Employing an F-102 vs. an F-22.
But this is about knives, specifically the Skyline. More specifically the way it opens, and the clip. Nutin and Jonnyf demonstrated that the knife can be opened easily and quickly either way. The flipper was intuitive to me but I can't effectively use the blade stops. John couldn't use either effectively in his video. I'll bet with a bit of practice, John and I both could use either as well as Jonnyf. Larger and lower thumb studs/blade stops would compromise weight and carry. Spring assist would compromise weight, carry and cost. A push button and a spring would compromise cost, shipping and where it could be carried. The clip issue is ridiculous. Clips can easily be loosened but difficult to tighten. They should all be too tight for the average Joe from the factory.
It's obviously not for everyone but the Skyline is a brilliant design optimizing cost and carry with a very slight compromise in that it takes a few minutes to learn how to use the flipper effectively.
John, take Tom's advice and learn to use the flipper; call the thumb studs blade stops and bend the clip out a bit or remove it. I guarantee you that only your ego will prevent you from admitting that the Skyline has to be one of the most cost effective, easiest carrying and deploying 3" blades in existence.
In answer to your original question; that's what nutin was thinking....