It depends on the grit and what happened to necessitate dressing. For the lower grits it would be using them with too much pressure so they no longer remove much metal. If you lighten up the pressure and use them a lot then the swarf will wear the resin and they will start to work properly again, but dressing is a whole lot faster and consistent. For the mid grits again too much pressure or they get loaded up too much for alcohol and a cloth to clean up. They may look clean but just don't cut the same. For the 2300 and especially the 4000 it is usually random deeper scratches, they still cut fine but leave random scratches in the bevel. I think this is larger pieces of debrise getting embedded in the resin but have never seen it in the stones under the microscope, but it wouldn't take much to cause those scratches.
If you keep the pressure light enough, what this is you will learn quick enough with some use, keep the swarf cleaned up between grits, use only edge trailing strokes, and take a few seconds to scrub the stones clean after using them in some water with your fingers, you should be able to go seveal hundred strokes before dressing even the 4k stone. I think the edge trailing strokes is a big deal especially for the finer grits. Under the microscope with the 4k stone with some knives I could see microchips in the apex with a deeper scratch where the chip got between the stone and bevel while doing an edge leading pass. Change to edge trailing passes and no more microchips. I think using edge trailing passes only does not just apply to the Matrix stones but to all stones so don't think this is an issue with Matrix stones only.
Ocelot85- Since that bevel is pretty wide I would try a little more pressure on the straight section of the blade to speed things up. How much pressure you can use depends on the surface area you are cutting, a thin bevel will be much less surface area so less pressure is in order. Do you have some sand to dress the 80 with, if you find you used too much pressure? I finally tried some of the 60 grit sic from EP and found it is not coarse enough to dress the 80, it needs something coarser.