A Manix 2? I’m thinking you’ve already tried one out, but it’s the first knife that comes to my mind when I think of ergonomics. I have average sized hands, though.
Another I don’t think I’ve seen listed is the ZT 0920. Looks plenty thick and hand filling, but I’ve never tried one personally.

Another I don’t think I’ve seen listed is the ZT 0920. Looks plenty thick and hand filling, but I’ve never tried one personally.