"Daylight" with Stallone featured a serrated Spyderco Endura FRN (first generation with the plastic clip).
"Hannibal" featured a SS Plain Edge Harpy, and I think Clarice Starling used a KCFF toward the end.
"Training Day" had a SS serrated Spyderco Police.
"Point of No Return" with Bridget Fonda and Harvey Kietel had a SS Spyderco Standard.
"Sudden Death" with Van Damme had a SS Spyderco Delica SE.
"Cliffhanger": SE FRN Endura (first generation)
"Windtalkers" had the KaBar marine knife
"Pitch Black": Riddick used various hand-made "Shivs", one of which he used to evicerate a monster.
"The Hunted" had the Tom Brown Tracker knife made by TOPS.
"The Bourne Identity": An assasin sent to kill Bourne uses a small push-dagger and some Kali.
"Men In Black": Tommy Lee Jones uses some auto to cut off an alien's disguise in the begining of the film.
"Gone in 60 Seconds"- The Sphinx character uses a large auto knife to pry open a fuse box. Maybe a Micro-tech??
"National Treasure": Nic Cages character flicks open some large drop-point folder to chisel way some loose bricks.
"The Da Vinci Code"-the evil Monk holds a woman hostage with maybe a CRKT Point-Guard.
"Gladiator" (Not the one with Russell Crowe, the one with Cuba Gooding Junior): Some thugs chase Cuba Gooding jr. and each one has a SS Endura.
"Kill Bill Volume 2": Buck 110 was used to cut a villian's achilles tendon.
"Behind Enemy Lines": Owen Wilson uses a Victorinox (red handles) for the screwdriver feature.
"Falling Down"-Michael Douglass' character stabs a Neo-Nazi with some Balisong/Butterfly knife that he took from a street thug earlier in the film.
"The Matrix Reloaded"- one of the Twins fights with a Straight Razor and cuts Trinity on the forearm with it.
"The Mummy Returns"- Brandon Fraser's character uses Balisong/Butterfly knife.
"Mr. And Mrs. Smith": Angelina Jolie uses some double-edged dagger.
"The Client"- Barry the Blade has an embelished SE Spyderco Police.
"The Punisher"-Emerson Kerambit (Satin blade), Spyderco Civilian (G-10).
"Strange Days": Milla Jovovich wields a Spyderco Mariner.
"Nip/Tuck (FX TV series) The Carver uses a cool looking Stainless Steel fixed blade.
I think the Spyderco Police and Endura models make the most frequent cameos out of all the production knives.